To understand how ORILISSA works, let’s start at the beginning

Endometriosis occurs when lesions grow outside the uterus.

What is endometriosis?

Endometriosis occurs when tissue that normally lines the inside of the uterus grows outside of the uterus (where it doesn't belong). It forms growths that are called lesions.

Endometriosis lesions grow as estrogen levels rise during your menstrual cycle.

Estrogen fuels endometriosis pain

Estrogen is a hormone that's naturally produced by your body. During your menstrual cycle, estrogen levels rise and can cause endometriosis lesions to grow. Then, during your period, the lesions can break down and shed, causing pain throughout the month.

One way to manage common symptoms of endometriosis is to reduce the amount of estrogen your body produces.

ORILISSA blocks GnRH receptors, which leads to decreased estrogen levels.

How does ORILISSA work?

ORILISSA is a pill that dials down estrogen. Lower estrogen levels can help manage endometriosis pain.

There are 2 doses of ORILISSA. Each dose lowers estrogen to a different level. Both the pain relief and any side effects you may experience could be different, depending on the dose you take and how your body responds. Your doctor will recommend the lowest effective dose based on your symptoms and treatment goals.

Make an appointment with your gynecologist today to see if ORILISSA could be right for you.

See ORILISSA in action

Watch this short video to see how ORILISSA works in your body.

Want to learn about ORILISSA's proven results?