Endometriosis occurs when tissue that normally lines the inside of the uterus grows outside of the uterus (where it doesn't belong). It forms growths that are called lesions.
Estrogen is a hormone that's naturally produced by your body. During your menstrual cycle, estrogen levels rise and can cause endometriosis lesions to grow. Then, during your period, the lesions can break down and shed, causing pain throughout the month.
One way to manage common symptoms of endometriosis is to reduce the amount of estrogen your body produces.
ORILISSA is different—it works in its own way. That's because it's a pill that dials down estrogen. Lower estrogen levels can help manage endometriosis pain.
There are 2 doses of ORILISSA. Each dose lowers estrogen to a different level. Both the pain relief and any side effects you may experience could be different, depending on the dose you take and how your body responds. Your doctor will recommend the lowest effective dose based on your symptoms and treatment goals.
Make an appointment with your gynecologist today to see if ORILISSA could be right for you.
My gynecologist explained that my endometriosis pain is triggered by something that my body naturally makes called estrogen. And, as long as my body keeps making estrogen, I'd be in pain. That's why she had recommended ORILISSA, because it's a pill that dials down estrogen to different levels depending on the dose you take."
Kellyn P.
Answer a few questions about your specific symptoms to help you talk to your gynecologist about it.
Rate your painEmily did not think ORILISSA would help relieve her endo pain. See how she changed her mind.
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Sign upORILISSA® (elagolix) is a prescription medicine used to treat moderate to severe pain associated with endometriosis. It is not known if ORILISSA is safe and effective in children under 18 years of age.
ORILISSA may cause serious side effects, including bone loss and effects on pregnancy:
Tell your HCP about all of your medical conditions, including if you:
Tell your HCP about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Especially tell your HCP if you take birth control pills. Your HCP may advise you to change the pills you take or your method of birth control.
ORILISSA can cause serious side effects including:
The most common side effects of ORILISSA include: hot flashes or night sweats, headache, nausea, difficulty sleeping, absence of periods, anxiety, joint pain, depression, and mood changes.
These are not all of the possible side effects of ORILISSA. This is the most important information to know about ORILISSA. For more information, talk to your doctor or HCP.
Take ORILISSA exactly as your HCP tells you. Tell your HCP if you have any side effect that bothers you or that does not go away. Call your HCP for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.
If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.
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Please click here for Full Prescribing Information and Medication Guide.