To understand how ORILISSA works in your body, let’s start at the beginning

What is endometriosis?

Endometriosis occurs when tissue similar to the endometrium—the tissue that lines the inside of the uterus—grows outside of the uterus where it doesn’t belong. These out-of-place growths are called lesions.


How do lesions grow and why do they cause pain?

Estrogen, a hormone that is naturally produced by your body, fuels the growth of endometrial lesions. During your menstrual cycle, when estrogen levels rise, these lesions can grow. And later, during your period, the lesions can break down and shed. This can cause pain throughout the month.

One way to manage common symptoms of endometriosis is to reduce the amount of estrogen your body produces. Learn more about endometriosis.

How does ORILISSA work?

ORILISSA is different than other endo pain treatments. It's a pill that works by dialing estrogen down. Lower estrogen levels can help manage endometriosis pain.

There are 2 doses of ORILISSA. Each dose dials estrogen down to a different level. Both the pain relief and any side effects you may experience could be different, depending on the dose you take and how your body responds. Your doctor will recommend the lowest effective dose based on your symptoms and treatment goals.

Make an appointment with your doctor today to see if ORILISSA could be right for you.