There has been a change to the Prescribing Information. Click here to see the changes and talk with your doctor for more information.
>One pill taken once a day, at about the same time each day, with or without food
OR
One pill taken twice a day, for a total of 400 mg a day, at about the same time each day, with or without food
AND
Your gynecologist will recommend the lowest effective dose based on your symptoms and treatment goals. Both the pain relief and any side effects you may experience could be different, depending on the dose you take and how your body responds.
Because ORILISSA works throughout your menstrual cycle, it’s important to take ORILISSA every day, exactly as your gynecologist prescribed—even if you’re feeling better. ORILISSA is not a medication you take only as needed.
It does not contain hormones and does not prevent pregnancy.
ORILISSA is a daily pill, so you and your gynecologist can decide to stop using it at any time.
The majority of women in clinical trials* who took either dose of ORILISSA got their period within a month after they stopped taking it (~60%, and ~95% got it within 6 months).
*These women had taken ORILISSA for 6 months.
Give us a call at 1-800-ORILISSA (1-800-674-5477). We’re here to answer questions you may have about ORILISSA.
Always ask your gynecologist. He or she knows you the best, and can help find the answers you’re looking for.
Get more info on ORILISSA and endometriosis to help make the most of your gynecologist's visit.
Sign UpFind out how you could be eligible to save* on your prescription with an Orilissa® Complete Savings Card.
*For eligible, commercially insured patients. Terms and Conditions apply. Click here to view them in full.
Want to know how ORILISSA works? Watch a video to learn more about how ORILISSA works in your body.
Watch videoORILISSA® (elagolix) is a prescription medicine used to treat moderate to severe pain associated with endometriosis. It is not known if ORILISSA is safe and effective in children under 18 years of age.
ORILISSA may cause serious side effects, including bone loss and effects on pregnancy:
Tell your HCP about all of your medical conditions, including if you:
Tell your HCP about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Especially tell your HCP if you take birth control pills. Your HCP may advise you to change the pills you take or your method of birth control.
ORILISSA can cause serious side effects including:
The most common side effects of ORILISSA include: hot flashes or night sweats, headache, nausea, difficulty sleeping, absence of periods, anxiety, joint pain, depression, and mood changes.
These are not all of the possible side effects of ORILISSA. This is the most important information to know about ORILISSA. For more information, talk to your doctor or HCP.
Take ORILISSA exactly as your HCP tells you. Tell your HCP if you have any side effect that bothers you or that does not go away. Call your HCP for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.
If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.
US-ORIL-200129
Please click here for Full Prescribing Information and Medication Guide.