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ORILISSA 150 mg
One pill taken once a day, at about the same time, with or without food
ORILISSA 200 mg
One pill taken twice a day, for a total of 400 mg a day, at about the same time each day, with or without food
Your doctor will recommend the lowest effective dose based on your symptoms and treatment goals. Both the pain relief and any side effects you experience may be different, depending on the dose you take.
Because ORILISSA works throughout your menstrual cycle, it’s important to take ORILISSA every day, exactly as your doctor prescribed—even if you’re feeling better. ORILISSA is not a medication you take only as needed.
It does not contain hormones and does not prevent pregnancy.
Before you take ORILISSA, tell your doctor about all of your medical conditions, including if you:
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Especially tell your doctor if you take birth control pills. Your doctor may advise you to change the pills you take, or your method of birth control.
Know the medicines you take. Keep a list of your medicines with you to show to your doctor and pharmacist when you get a new medicine.
Bone mineral density (BMD)
ORILISSA may change your menstrual periods (irregular bleeding or spotting, a decrease in menstrual bleeding, or no bleeding at all), making it hard to know if you are pregnant. Watch for other signs of pregnancy such as breast tenderness, weight gain and nausea.
Importance of birth control
ORILISSA is not birth control and does not prevent pregnancy. You will need to use effective methods of birth control that do not contain hormones such as condoms or spermicide while taking ORILISSA and for one week after you stop taking ORILISSA. Birth control pills that contain estrogen may make ORILISSA less effective. It is not known how well ORILISSA will work while you are taking progestin-only birth control.
ORILISSA does not contain hormones. Talk to your doctor about which birth control to use during treatment with ORILISSA. Your doctor may change the birth control you were on before you start taking ORILISSA.
The impact of ORILISSA on breast milk and the nursing baby is not known. Talk to your doctor about the best way to feed your baby if you take ORILISSA.
Other quick answers and tips
If you miss a dose, take it as soon as you remember as long as it is on the same day. You should then continue your regular dosing schedule.
Do not take more than 1
pill each day.
Do not take more than 2 pills
(400 mg total) each day.
If you take too much ORILISSA, call your doctor or go to the nearest hospital.
ORILISSA does not prevent pregnancy. You'll need to use effective non-hormonal methods of birth control such as condoms or spermicide while taking ORILISSA. Birth control pills that contain estrogen may affect how well ORILISSA works. It is not known how well ORILISSA will work while you are taking progestin-only birth control. Talk to your doctor about which birth control to use during your treatment. Your doctor may change the birth control you were on before starting ORILISSA.
Store ORILISSA between 36°F to 86°F (2°C to 30°C). Keep ORILISSA and all medicines out of the reach of children.
If your doctor prescribed you ORILISSA 200 mg, take one ORILISSA 200 mg pill in the morning and one ORILISSA 200 mg pill in the evening (400 mg total).
If you’ve still got questions about ORILISSA, you can:
Rate your pain so you can have a more informed conversation with your doctor at your next appointment.