What is ORILISSA

WHAT IS ORILISSA?

ORILISSA—made for moderate to severe endometriosis pain

ORILISSA is the first FDA-approved oral pill specifically developed for women with moderate to severe endometriosis pain in over a decade.
It’s a prescription medication available in 2 doses. And, depending on the dose, ORILISSA may reduce 3 common types of endometriosis pain:

  • Painful periods: doctors call this dysmenorrhea (DIS-men-uh-REE-uh)
  • Pelvic pain in between periods: doctors call this non-menstrual pelvic pain
  • Pain with sex*: doctors call this dyspareunia (DIS-puh-ROO-nee-uh)

*Only the 200 mg dose was proven to work for pain with sex. The ORILISSA 150 mg dose didn’t show a significant difference in reported pain with sex compared with placebo (a pill with no active medicine).

ORILISSA is FDA-approved for the management of moderate to severe endometriosis pain in women.

It was studied in clinical trials of 1686 women with moderate to severe endometriosis pain ranging in age from 18 to 49—the largest endometriosis clinical trial program to date.