What is ORILISSA

WHAT IS ORILISSA?

ORILISSA—made for moderate to severe endometriosis pain

ORILISSA is the first FDA-approved pill specifically developed for women with moderate to severe endometriosis pain in over a decade. Doctors have already prescribed it to over 20,000 women.

ORILISSA was proven to relieve:

  • Painful periods: doctors call this dysmenorrhea (DIS-men-uh-REE-uh)
  • Pelvic pain in between periods: doctors call this non-menstrual pelvic pain
  • Pain with sex*: doctors call this dyspareunia (DIS-puh-ROO-nee-uh)

*There are 2 different doses of ORILISSA: 150 mg (taken once a day) or 200 mg (taken twice a day). Only the 200 mg dose was proven to work for pain with sex.

Make an appointment today and ask your doctor if ORILISSA could be right for you.

ORILISSA was made for endometriosis pain

It works by lowering the amount of estrogen in the body, and estrogen fuels painful endometriosis lesions.

Less estrogen = less fuel for painful endo lesions


ORILISSA is available in 2 different doses. Each dose lowers estrogen by different amounts so you and your gynecologist can choose which dose is best for your individual needs.

Estrogen is a hormone that exists naturally in the body.