See ORILISSA in action
Want to know how ORILISSA works? Watch a video to learn more about how ORILISSA works in your body.
Watch videoSafety Information Update
There has been a change to the Prescribing Information. Click here to see the changes and talk with your doctor for more information.
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ORILISSA STORIES
AND REVIEWS
There are women with moderate to severe endometriosis pain out there just like you… watch their stories.
Video Library
ORILISSA—Proven to relieve endometriosis pain
Discover the benefits of ORILISSA, proven in the largest endometriosis clinical trial program to date.
Experiencing endo pain?
Create a guide to help you talk to your doctor about your pain.
Rate your pain
Discover the proven results of ORILISSA
The benefits of ORILISSA were proven in the largest endometriosis clinical trial program to date.
See the resultsUSE
ORILISSA® (elagolix) is a prescription medicine used to treat moderate to severe pain associated with endometriosis. It is not known if ORILISSA is safe and effective in children under 18 years of age.
IMPORTANT SAFETY INFORMATION
What is the most important information I should know about ORILISSA?
ORILISSA may cause serious side effects, including bone loss and effects on pregnancy:
- Bone Loss (decreased Bone Mineral Density [BMD])
While you are taking ORILISSA, your estrogen levels will be low. This can lead to BMD loss. Your BMD may improve after stopping ORILISSA, but may not recover completely. It is unknown if these bone changes could increase your risk for broken bones as you age. Your healthcare provider (HCP) may order a DXA scan to check your BMD. - Effects on Pregnancy
Do not take ORILISSA if you are trying to become or are pregnant, as your risk for early pregnancy loss may increase. If you think you are pregnant, stop taking ORILISSA right away and call your HCP. ORILISSA may change your menstrual periods (irregular bleeding or spotting, a decrease in menstrual bleeding, or no bleeding at all), making it hard to know if you are pregnant. Watch for other signs of pregnancy, such as breast tenderness, weight gain, and nausea. ORILISSA does not prevent pregnancy. You will need to use effective hormone-free birth control (such as condoms or spermicide) while taking ORILISSA and for one week after stopping ORILISSA. Birth control pills that contain estrogen may make ORILISSA less effective. It is unknown how well ORILISSA works while on progestin-only birth control.
Do not take ORILISSA if you:
- Are or may be pregnant, have osteoporosis, have severe liver disease, or take medicines known as strong OATP1B1 inhibitors, such as cyclosporine or gemfibrozil. If you are unsure if you are taking one of these medicines, ask your HCP.
What should I tell my HCP before taking ORILISSA?
Tell your HCP about all of your medical conditions, including if you:
- Have or have had broken bones, have other conditions, or take medicines that may cause bone problems; have or have had depression, mood problems, or suicidal thoughts or behavior; have liver problems; think you may be pregnant; or are breastfeeding or plan to be. It is unknown if ORILISSA passes into breast milk. Talk to your HCP about the best way to feed your baby if you take ORILISSA.
Tell your HCP about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Especially tell your HCP if you take birth control pills. Your HCP may advise you to change the pills you take or your method of birth control.
What are the possible side effects of ORILISSA?
ORILISSA can cause serious side effects including:
- Suicidal thoughts, actions, or behavior, and worsening of mood. Call your HCP right away, or call 911 if an emergency, if you have any of these symptoms, especially if they are new, worse, or bother you: thoughts about suicide or dying, try to commit suicide, new or worse depression or anxiety, or other unusual changes in behavior or mood. You or your caregiver should pay attention to any changes, especially sudden changes in your mood, behaviors, thoughts, or feelings.
- Abnormal liver tests. Call your HCP right away if you have any of these signs and symptoms of liver problems: yellowing of the skin or the whites of the eyes (jaundice), dark amber-colored urine, feeling tired, nausea and vomiting, generalized swelling, right upper stomach area pain, or bruising easily.
The most common side effects of ORILISSA include: hot flashes or night sweats, headache, nausea, difficulty sleeping, absence of periods, anxiety, joint pain, depression, and mood changes.
These are not all of the possible side effects of ORILISSA. This is the most important information to know about ORILISSA. For more information, talk to your doctor or HCP.
Take ORILISSA exactly as your HCP tells you. Tell your HCP if you have any side effect that bothers you or that does not go away. Call your HCP for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.
If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.
US-ORIL-200129
Please click here for Full Prescribing Information and Medication Guide.
Brit T.'s Story
"After being on ORILISSA for 3 months, my endo pain’s gone down!”
My pelvic pain began as a teenager. My mother and grandmother had similar symptoms and were both diagnosed with endometriosis, which left me wondering if my pelvic pain could be caused by endometriosis, too.
For 10 years, I simply dealt with the constant pain—both during my period and throughout the month—but then, I hit a breaking point. I was working my dream job, but I was having trouble hiding my pain at work. I decided I needed to do something.
I changed physicians and finally found a gynecologist who I trusted. We had a conversation about my medical history and he did an exam and clinically diagnosed me with endometriosis. Immediately he told me about ORILISSA, and I decided to give it a try.
With ORILISSA, my periods have been less painful. I hope women talk to their gynecologists to see if ORILISSA could be right for their endometriosis pain. For me—ORILISSA was the right choice.
Amy Z.'s Story
"I think women should talk to their GYNs and ask about ORILISSA. Maybe they won’t have to put up with the kind of endometriosis pain that I stayed silent about for years.”
After dealing with severe pelvic pain for as long as I can remember, I was finally diagnosed with endometriosis at 38. I spent the next few years putting on a smile and pushing through my pain. I’m a kindergarten teacher’s assistant, so it’s my job to inspire a love of learning in my students from an early age. But it was challenging for me to bring that excitement to the classroom each day while struggling with debilitating pelvic pain.
I didn’t know what to do. I’d tried treatment options that worked for others, but they didn’t work for me. And, surgery wasn’t an option for me either. So, I felt stuck. That’s when I scheduled another appointment with my gynecologist. She told me about an option that might help my endometriosis pain—ORILISSA.
We talked all about it and weighed the benefits against the potential side effects. Together, we decided that I should try it. And I’m so glad I did. Since taking ORILISSA, I have less endometriosis pain. I hope by sharing my story, I can encourage other women to speak up and talk to their gynecologists about their options.
Hannah M.'s Story
"On ORILISSA, I have less endometriosis pain. And I hope that by sharing my story, I can help other women who feel like their voices have been silenced.”
I was diagnosed with endometriosis at age 23 after searching for answers for 7 years. I was experiencing painful periods and stabbing pelvic pain in between my periods for so long. And I went to gynecologist after gynecologist, but I still didn’t have a name for my pain, and it made me feel like it wasn’t valid.
I finally got a new referral, but the voice in my head kept saying, “She’s just going to be like everyone else…” I wasn’t sure it was worth it, but I decided to give it a shot and made an appointment. The second I sat down, I could sense something was different, and it felt like she genuinely wanted to help me.
She asked me about my symptoms, and her warm presence helped me to open up. I told her everything—the revolving door of doctors, and how I struggled with even the little things because of my endometriosis pain, like taking my dog, George, for walks. And as I shared my pain, I started crying, because I realized I had finally found a gynecologist who heard me—I felt like I had a voice again.
She scheduled a surgical procedure to help me get a diagnosis. And sure enough, it confirmed that I had endometriosis. Although I was relieved to finally have a name for my pain, it was a lot to take in that I had a long-term health condition.
My gynecologist and I talked about a few options for treatment, and that’s when she suggested ORILISSA. We talked about how it works and she answered all my questions. Then, I decided to give it a try. And I’m so glad I did because, on ORILISSA, I have less pain in between my periods and during my period, too.
I learned how important it is to trust myself and keep speaking up because that’s how I got the help I needed. I hope that by sharing my story, I can inspire other women who feel like their voices have been silenced.
Angela S.'s Story
"After taking ORILISSA for a while, I woke up one morning and realized that something’s different. Oh, I’m not in as much pain.”
I’m 39 years old and was diagnosed with endometriosis at 25, after struggling for 12 years. I experienced pelvic pain and cramps and tried to treat it with various forms of birth control (pills, IUD, and injections) and various prescription painkillers.
The pain affected so many aspects of my life, but especially the time I spent with my friends and family. I couldn’t fully enjoy family outings, and I kept having to cancel on my friends.
With ORILISSA, I was in less endo pain. Being in less pain allowed me to get back to doing some of the things I love—like cooking and spending more time with my daughters. I hope sharing my story will help other women learn about ORILISSA and encourage them to be more outspoken about their endo pain and need for treatment options.
Kat C.'s Story
"With ORILISSA, my endo pain is better. There’s a whole world out there. And I’m diving in.”
My name's Kat and I was diagnosed with endometriosis when I was 28. A year before that, I noticed a change when my periods became really painful and I even started having pelvic pain in between my periods. There were times when it felt like a cheese grater was just scraping me raw.
I mentioned it to my gynecologist, but I wasn’t ready to do anything about it. The pain would come and go and I just sort of hoped it would go away. But it didn’t…it only got worse. Finally, I realized I couldn’t just manage it on my own. So, I made a new appointment with my gynecologist. And this time, I was ready to prioritize my pain and get to the bottom of it.
Before the appointment, I took the time to make a list of all my symptoms—even the little things that didn’t seem like they’d matter—and brought it with me. It actually helped start the conversation. And it helped my gynecologist understand my situation better than if I had just tried to explain things on my own.
After discussing the list, she gave me a pelvic exam and diagnosed me with endometriosis that day. Then we talked about treatments for my endometriosis pain. One option was surgery, which I know is right for some women, but I really didn’t want it. But there was another option she recommended—a pill called ORILISSA—that I was excited to learn about. We decided to give it a try and I’m glad we did because on ORILISSA, I have less pain.
At first, I wasn’t sure if making that list of symptoms would help. But it turns out, it’s what got the ball rolling and led to my diagnosis and ORILISSA. That’s why I volunteered to tell my story. To let you know that whether you’ve got a new gynecologist or one you’ve known for years, sharing every detail, even ones that feel unimportant, can help get answers. If you’re not sure where to start, make a list. It may not seem like a big deal, but it can make a big difference.
Gillian L.'s Story
"ORILISSA is worth talking to your gynecologist about. It worked for me. Maybe it could for you, too.”
I began experiencing painful periods at 12 years old. At age 16, I was put on birth control and took over-the-counter painkillers for my “bad periods.” Two years later, I stumbled upon an article about endometriosis—it made me wonder if what I had was more than just cramps. My suspicions were confirmed when I was officially diagnosed with endometriosis at 21.
After that, I tried different types of birth control and injections. Although they work for some women, none of these treatments worked for my endometriosis pain.
Then, my gynecologist told me about ORILISSA. We talked about it and it sounded like the right option for me.
3 months after taking ORILISSA, I was out shopping with my mom when suddenly I realized—my pain wasn’t hurting like it used to. I didn’t have to stop and take breaks for my pain to subside. That was the moment I knew ORILISSA worked for me. With ORILISSA, I felt endometriosis pain relief. The cramping feeling lessened and my everyday pain decreased.
I’m passionate about sharing my ORILISSA experience and I want to encourage others to talk to their gynecologists to see if it could be right for them.
Cassandra H.'s Story
"On ORILISSA, my pelvic pain has gone down. And I can’t tell you how much it means to me.”
I’ve struggled with debilitating pelvic pain since I was 11 years old. When I was 18, the pain was so bad that I passed out. I was rushed to the emergency room and that’s when I was diagnosed with endometriosis. I was relieved to find out there was a reason for my pain, but the gynecologist’s vague description of how to manage my painful symptoms left me confused.
I saw so many gynecologists who all recommended various kinds of birth control and over-the-counter pain medications. But nothing seemed to help my endometriosis pain. I didn’t know what to do and I didn’t know who to turn to. Luckily my mom saw that I was struggling and suggested we see a new gynecologist who was recommended to her. Her office was kind of far from where we lived, but we decided it was worth it, even if we had to travel a bit for the appointment.
This gynecologist took my endometriosis pain seriously and suggested I try ORILISSA. I had never heard of it, so I went home and did a lot of research and saw that over a thousand women were in the clinical trials. At my next appointment, we talked more and decided it was something I should try. I’m glad I did—with ORILISSA, my endometriosis pain’s gone down. And that’s something I want to share with others.
Brit T.'s Story
"After being on ORILISSA for 3 months, my endo pain’s gone down!”
My pelvic pain began as a teenager. My mother and grandmother had similar symptoms and were both diagnosed with endometriosis, which left me wondering if my pelvic pain could be caused by endometriosis, too.
For 10 years, I simply dealt with the constant pain—both during my period and throughout the month—but then, I hit a breaking point. I was working my dream job, but I was having trouble hiding my pain at work. I decided I needed to do something.
I changed physicians and finally found a gynecologist who I trusted. We had a conversation about my medical history and he did an exam and clinically diagnosed me with endometriosis. Immediately he told me about ORILISSA, and I decided to give it a try.
With ORILISSA, my periods have been less painful. I hope women talk to their gynecologists to see if ORILISSA could be right for their endometriosis pain. For me—ORILISSA was the right choice.
Amy Z.'s Story
"I think women should talk to their GYNs and ask about ORILISSA. Maybe they won’t have to put up with the kind of endometriosis pain that I stayed silent about for years.”
After dealing with severe pelvic pain for as long as I can remember, I was finally diagnosed with endometriosis at 38. I spent the next few years putting on a smile and pushing through my pain. I’m a kindergarten teacher’s assistant, so it’s my job to inspire a love of learning in my students from an early age. But it was challenging for me to bring that excitement to the classroom each day while struggling with debilitating pelvic pain.
I didn’t know what to do. I’d tried treatment options that worked for others, but they didn’t work for me. And, surgery wasn’t an option for me either. So, I felt stuck. That’s when I scheduled another appointment with my gynecologist. She told me about an option that might help my endometriosis pain—ORILISSA.
We talked all about it and weighed the benefits against the potential side effects. Together, we decided that I should try it. And I’m so glad I did. Since taking ORILISSA, I have less endometriosis pain. I hope by sharing my story, I can encourage other women to speak up and talk to their gynecologists about their options.
Kellyn P.'s Story
“I talked to my gynecologist and then I did my own research, and this helped me make the decision to give ORILISSA a chance.”
I had really painful periods as soon as I first got my period at age 10. As I got older, I was prescribed various forms of birth control to help with the pain, but was not actually diagnosed with endometriosis.
A few years later, I saw a different gynecologist who diagnosed with me endometriosis. I felt kind of relieved because finally, I knew it wasn’t all in my head and I wasn’t crazy.
After that appointment, I was treated with other medications and surgery, but there were still days where I struggled to go to work or school 'cause of my pelvic pain. I really thought this much endo pain was just going to be my normal.
I switched to another gynecologist a few years later, and she told me about ORILISSA. She explained to me how it worked, the benefits and potential risks, and how she had prescribed it for some of her other patients with endometriosis pain. She thought it could help, but I had doubts. I asked a lot of questions and then went home and did my own research into the benefits and potential side effects of the medication. This helped me decide to give it a try. With ORILISSA, I’m not in as much pain.
I want to say to other women who are struggling with their endo pain, ask questions, seek a second opinion if you feel you need to, don’t give up 'cause your pain isn’t normal and you don’t have to suffer in silence.
Meghan M.'s Story
"On ORILISSA, I move through life with less endometriosis pain and I’m not looking back.”
For 10 years, I suffered through painful periods and pelvic pain—it felt like someone was constantly pinching and pulling my uterus. After an emergency surgery, I was diagnosed with endometriosis. For the next several years, I was prescribed birth control to manage my endometriosis pain, but the pain persisted.
Over time, my pelvic pain got worse and I became more frustrated. Nothing seemed to work and I felt like I was running out of options. That’s when my gynecologist suggested ORILISSA. I was interested, so I decided to do my own research and see what I could find.
After posting on social media about it, I heard many different opinions, and some were not so great. Some of the responses even made me feel bullied. So, I went back to my gynecologist to ask about what I was reading online. He explained everything I needed to know about ORILISSA, including the benefits and the risks. And after a long discussion, I decided it was the right option for me to try.
I’m so happy I decided to try it because it reduced my endometriosis pain. I want to share my experience on ORILISSA, encourage other women to do their own research, and speak with their gynecologist, instead of just listening to what people say on social media.
Sara S.'s Story
“My mom reminded me, it’s not normal to be in this much pain. So, if there’s even a small chance ORILISSA could help with my endo pain, she thought I should really consider it.”
I used to believe that my painful periods were normal. I honestly thought I was having typical period cramps and all women went through the same thing. I didn’t recognize that periods were not supposed to be that painful. At times, mine kept me from going out with friends because socializing in that way felt like a risk. I was always worried that my pelvic pain would distract me and so it didn’t really feel worth it.
In 2019 I was officially diagnosed with endometriosis and that’s when my gynecologist recommended I try ORILISSA for my pain. At first, I thought "that’s not for me." But when I went home and told my mom about it, she reminded me of the challenges that I had in the past with endometriosis pain. She told me being in this much endo pain is not normal and I really owed it to myself to see if ORILISSA could work.
After a few months of being on ORILISSA, my pain during my periods and pain between my periods has really improved. I have the experience now to say don’t just assume your pain is normal and I want to be that voice for other women. Go talk to a gynecologist about what you’re going through and don’t give up on exploring your treatment choices for your pain.
Emily S.'s Story
“I was afraid to get my hopes up, but I thought to myself, ‘if there’s something that could help you find some pain relief, wouldn’t you want to try it?’”
My struggle with endometriosis pain started when I was 11. I started having intensely painful periods and pain in between my periods that only seemed to get worse over the years as I got older. But it also just became part of my normal day-to-day life – dealing with the pain.
I was hesitant about some of the treatment options my gynecologist had recommended in the past, like surgery. But, after a really painful period, I decided I needed to see my doctor again and discuss a change to what I was doing for my pain. I felt like I owed it to myself to try to find a way to live with less pain. That’s when he recommended and prescribed ORILISSA for me. I walked away skeptical that it would actually work but was willing to give it a chance. I dove in!
After being on ORILISSA for a few months, my endometriosis pain has noticeably improved. I really recommend talking to your doctor if you are suffering like I was with endometriosis pain. Your pain is real. Don’t give up because there may be help to be found.
Kellyn P.'s Story
“I talked to my gynecologist and then I did my own research, and this helped me make the decision to give ORILISSA a chance.”
I had really painful periods as soon as I first got my period at age 10. As I got older, I was prescribed various forms of birth control to help with the pain, but was not actually diagnosed with endometriosis.
A few years later, I saw a different gynecologist who diagnosed with me endometriosis. I felt kind of relieved because finally, I knew it wasn’t all in my head and I wasn’t crazy.
After that appointment, I was treated with other medications and surgery, but there were still days where I struggled to go to work or school 'cause of my pelvic pain. I really thought this much endo pain was just going to be my normal.
I switched to another gynecologist a few years later, and she told me about ORILISSA. She explained to me how it worked, the benefits and potential risks, and how she had prescribed it for some of her other patients with endometriosis pain. She thought it could help, but I had doubts. I asked a lot of questions and then went home and did my own research into the benefits and potential side effects of the medication. This helped me decide to give it a try. With ORILISSA, I’m not in as much pain.
I want to say to other women who are struggling with their endo pain, ask questions, seek a second opinion if you feel you need to, don’t give up 'cause your pain isn’t normal and you don’t have to suffer in silence.
Meghan M.'s Story
"On ORILISSA, I move through life with less endometriosis pain and I’m not looking back.”
For 10 years, I suffered through painful periods and pelvic pain—it felt like someone was constantly pinching and pulling my uterus. After an emergency surgery, I was diagnosed with endometriosis. For the next several years, I was prescribed birth control to manage my endometriosis pain, but the pain persisted.
Over time, my pelvic pain got worse and I became more frustrated. Nothing seemed to work and I felt like I was running out of options. That’s when my gynecologist suggested ORILISSA. I was interested, so I decided to do my own research and see what I could find.
After posting on social media about it, I heard many different opinions, and some were not so great. Some of the responses even made me feel bullied. So, I went back to my gynecologist to ask about what I was reading online. He explained everything I needed to know about ORILISSA, including the benefits and the risks. And after a long discussion, I decided it was the right option for me to try.
I’m so happy I decided to try it because it reduced my endometriosis pain. I want to share my experience on ORILISSA, encourage other women to do their own research, and speak with their gynecologist, instead of just listening to what people say on social media.
Sara S.'s Story
“My mom reminded me, it’s not normal to be in this much pain. So, if there’s even a small chance ORILISSA could help with my endo pain, she thought I should really consider it.”
I used to believe that my painful periods were normal. I honestly thought I was having typical period cramps and all women went through the same thing. I didn’t recognize that periods were not supposed to be that painful. At times, mine kept me from going out with friends because socializing in that way felt like a risk. I was always worried that my pelvic pain would distract me and so it didn’t really feel worth it.
In 2019 I was officially diagnosed with endometriosis and that’s when my gynecologist recommended I try ORILISSA for my pain. At first, I thought "that’s not for me." But when I went home and told my mom about it, she reminded me of the challenges that I had in the past with endometriosis pain. She told me being in this much endo pain is not normal and I really owed it to myself to see if ORILISSA could work.
After a few months of being on ORILISSA, my pain during my periods and pain between my periods has really improved. I have the experience now to say don’t just assume your pain is normal and I want to be that voice for other women. Go talk to a gynecologist about what you’re going through and don’t give up on exploring your treatment choices for your pain.
Kat C.'s Story
"With ORILISSA, my endo pain is better. There’s a whole world out there. And I’m diving in.”
My name's Kat and I was diagnosed with endometriosis when I was 28. A year before that, I noticed a change when my periods became really painful and I even started having pelvic pain in between my periods. There were times when it felt like a cheese grater was just scraping me raw.
I mentioned it to my gynecologist, but I wasn’t ready to do anything about it. The pain would come and go and I just sort of hoped it would go away. But it didn’t…it only got worse. Finally, I realized I couldn’t just manage it on my own. So, I made a new appointment with my gynecologist. And this time, I was ready to prioritize my pain and get to the bottom of it.
Before the appointment, I took the time to make a list of all my symptoms—even the little things that didn’t seem like they’d matter—and brought it with me. It actually helped start the conversation. And it helped my gynecologist understand my situation better than if I had just tried to explain things on my own.
After discussing the list, she gave me a pelvic exam and diagnosed me with endometriosis that day. Then we talked about treatments for my endometriosis pain. One option was surgery, which I know is right for some women, but I really didn’t want it. But there was another option she recommended—a pill called ORILISSA—that I was excited to learn about. We decided to give it a try and I’m glad we did because on ORILISSA, I have less pain.
At first, I wasn’t sure if making that list of symptoms would help. But it turns out, it’s what got the ball rolling and led to my diagnosis and ORILISSA. That’s why I volunteered to tell my story. To let you know that whether you’ve got a new gynecologist or one you’ve known for years, sharing every detail, even ones that feel unimportant, can help get answers. If you’re not sure where to start, make a list. It may not seem like a big deal, but it can make a big difference.
Angela S.'s Story
"After taking ORILISSA for a while, I woke up one morning and realized that something’s different. Oh, I’m not in as much pain.”
I’m 39 years old and was diagnosed with endometriosis at 25, after struggling for 12 years. I experienced pelvic pain and cramps and tried to treat it with various forms of birth control (pills, IUD, and injections) and various prescription painkillers.
The pain affected so many aspects of my life, but especially the time I spent with my friends and family. I couldn’t fully enjoy family outings, and I kept having to cancel on my friends.
With ORILISSA, I was in less endo pain. Being in less pain allowed me to get back to doing some of the things I love—like cooking and spending more time with my daughters. I hope sharing my story will help other women learn about ORILISSA and encourage them to be more outspoken about their endo pain and need for treatment options.
Hannah M.'s Story
"On ORILISSA, I have less endometriosis pain. And I hope that by sharing my story, I can help other women who feel like their voices have been silenced.”
I was diagnosed with endometriosis at age 23 after searching for answers for 7 years. I was experiencing painful periods and stabbing pelvic pain in between my periods for so long. And I went to gynecologist after gynecologist, but I still didn’t have a name for my pain, and it made me feel like it wasn’t valid.
I finally got a new referral, but the voice in my head kept saying, “She’s just going to be like everyone else…” I wasn’t sure it was worth it, but I decided to give it a shot and made an appointment. The second I sat down, I could sense something was different, and it felt like she genuinely wanted to help me.
She asked me about my symptoms, and her warm presence helped me to open up. I told her everything—the revolving door of doctors, and how I struggled with even the little things because of my endometriosis pain, like taking my dog, George, for walks. And as I shared my pain, I started crying, because I realized I had finally found a gynecologist who heard me—I felt like I had a voice again.
She scheduled a surgical procedure to help me get a diagnosis. And sure enough, it confirmed that I had endometriosis. Although I was relieved to finally have a name for my pain, it was a lot to take in that I had a long-term health condition.
My gynecologist and I talked about a few options for treatment, and that’s when she suggested ORILISSA. We talked about how it works and she answered all my questions. Then, I decided to give it a try. And I’m so glad I did because, on ORILISSA, I have less pain in between my periods and during my period, too.
I learned how important it is to trust myself and keep speaking up because that’s how I got the help I needed. I hope that by sharing my story, I can inspire other women who feel like their voices have been silenced.
Meghan M.'s Story
"On ORILISSA, I move through life with less endometriosis pain and I’m not looking back.”
For 10 years, I suffered through painful periods and pelvic pain—it felt like someone was constantly pinching and pulling my uterus. After an emergency surgery, I was diagnosed with endometriosis. For the next several years, I was prescribed birth control to manage my endometriosis pain, but the pain persisted.
Over time, my pelvic pain got worse and I became more frustrated. Nothing seemed to work and I felt like I was running out of options. That’s when my gynecologist suggested ORILISSA. I was interested, so I decided to do my own research and see what I could find.
After posting on social media about it, I heard many different opinions, and some were not so great. Some of the responses even made me feel bullied. So, I went back to my gynecologist to ask about what I was reading online. He explained everything I needed to know about ORILISSA, including the benefits and the risks. And after a long discussion, I decided it was the right option for me to try.
I’m so happy I decided to try it because it reduced my endometriosis pain. I want to share my experience on ORILISSA, encourage other women to do their own research, and speak with their gynecologist, instead of just listening to what people say on social media.
Sarah J.'s Story
"ORILISSA is a medication that women struggling with endometriosis pain should know about.”
I remember my first period at 11 years old being painful. Over the next 5 years, that pain only got worse. My doctor prescribed birth control to see if that would help, but it didn’t. By age 21, my pelvic pain became so debilitating that there were days I struggled to get out of bed. I went back to my doctor in hope of answers.
Eventually, I was referred to a new gynecologist who diagnosed me with endometriosis. I felt so relieved. People had told me that my pain was in my head, but now I finally had a diagnosis that proved it was real.
Following my diagnosis, my gynecologist and I tried many treatment options to relieve my endometriosis pain. But sometimes it still affected me when it came to making plans or going to work. It was frustrating. So, I went back to my gynecologist and told him I needed another option. That’s when he recommended ORILISSA.
Since taking ORILISSA, my endometriosis pain has decreased. I’m excited to share my ORILISSA story and hope that other women who are suffering will talk to their gynecologists about this treatment option.
Gillian L.'s Story
"ORILISSA is worth talking to your gynecologist about. It worked for me. Maybe it could for you, too.”
I began experiencing painful periods at 12 years old. At age 16, I was put on birth control and took over-the-counter painkillers for my “bad periods.” Two years later, I stumbled upon an article about endometriosis—it made me wonder if what I had was more than just cramps. My suspicions were confirmed when I was officially diagnosed with endometriosis at 21.
After that, I tried different types of birth control and injections. Although they work for some women, none of these treatments worked for my endometriosis pain.
Then, my gynecologist told me about ORILISSA. We talked about it and it sounded like the right option for me.
3 months after taking ORILISSA, I was out shopping with my mom when suddenly I realized—my pain wasn’t hurting like it used to. I didn’t have to stop and take breaks for my pain to subside. That was the moment I knew ORILISSA worked for me. With ORILISSA, I felt endometriosis pain relief. The cramping feeling lessened and my everyday pain decreased.
I’m passionate about sharing my ORILISSA experience and I want to encourage others to talk to their gynecologists to see if it could be right for them.
Darby D.'s Story
"Going from a life of pain every day to a lot less endometriosis pain, it is easier to do more of the things I love.”
I was diagnosed with endometriosis at 22, after dealing with severe pelvic pain for 6 years. I tried various forms of birth control and had 2 surgeries—neither did much to help my pain.
I was so fed up that, at only 34 years old, I asked my gynecologist if I should have a hysterectomy. That’s when he told me about a totally different option—a pill called ORILISSA!
On ORILISSA, I have less pain. This lets me get back to things I love, like working out and playing softball. I hope my experience empowers other women and gives them hope that there are other options out there.
Sarah J.'s Story
"ORILISSA is a medication that women struggling with endometriosis pain should know about.”
I remember my first period at 11 years old being painful. Over the next 5 years, that pain only got worse. My doctor prescribed birth control to see if that would help, but it didn’t. By age 21, my pelvic pain became so debilitating that there were days I struggled to get out of bed. I went back to my doctor in hope of answers.
Eventually, I was referred to a new gynecologist who diagnosed me with endometriosis. I felt so relieved. People had told me that my pain was in my head, but now I finally had a diagnosis that proved it was real.
Following my diagnosis, my gynecologist and I tried many treatment options to relieve my endometriosis pain. But sometimes it still affected me when it came to making plans or going to work. It was frustrating. So, I went back to my gynecologist and told him I needed another option. That’s when he recommended ORILISSA.
Since taking ORILISSA, my endometriosis pain has decreased. I’m excited to share my ORILISSA story and hope that other women who are suffering will talk to their gynecologists about this treatment option.
Joanna K.'s Story
"Endometriosis can be a long and winding road. But now with ORILISSA, I’m in less pain and I’m ready to ride.”
When I was 22, I was diagnosed with endometriosis. I was relieved to get a diagnosis, but I still had questions…What now? How could I manage my endometriosis pain? Was it just something I would always have to deal with? It’s not like getting diagnosed suddenly made the pain go away. It was still there, always lurking.
For instance, my husband and I love riding motorcycles together. The open road would usually take my mind off things. But now, the bike just made my endometriosis pain worse—all the twists and turns were unbearable. And it was tough for me to enjoy our trips together. All I could think about was my pelvic pain.
I also had pain with sex, which was awful—it turned sex into something I dreaded. And I felt like, when we did have sex, I just couldn’t stay present. At first, I tried to hide the pain, but the longer we were married, I couldn't fake how I felt.
So, for about 13 years, I tried managing my symptoms with birth control and surgery, but it didn’t really help my endometriosis pain. Finally, I reached my breaking point and decided to go back to my gynecologist to talk about trying something else. That’s when he suggested I try ORILISSA—he told me that it’s the only pill that's clinically proven to relieve moderate to severe endometriosis pain. It was so exciting! It gave me hope for, not just me, but other women with endo pain, too.
I'm so grateful that my gynecologist suggested ORILISSA because it worked for me—it reduced the pain I had with sex, the pain during my periods, and the pain in between my periods, too. And that’s why I’m sharing my story here. Maybe it can help other women speak up and find an option that works for them.