[LOGO]

[Text on Screen]
What is ORILISSA?
ORILISSA is a prescription medicine used to treat moderate to severe pain associated with endometriosis. It is not known if ORILISSA is safe and effective in children.

Do not take ORILISSA if you:
Are pregnant, have osteoporosis, have severe liver disease, are taking medicines called OATP 1B1 inhibitors that are known or expected to significantly increase the blood levels of elagolix, the active ingredient in ORILISSA (ask your HCP if you are not sure if you are taking one of these medicines), or have had a serious allergic reaction to ORILISSA or any of the ingredients in ORILISSA. See the end of the Medication Guide for a complete list of ingredients in ORILISSA. Ask your HCP if you are not sure.

Please see additional Important Safety Information and the Full Prescribing Information, including Medication Guide, on this website.

[Text on Screen]
Darby’s ORILISSA STORY

Individual results may vary.

DARBY:
My name’s Darby. I am from South Carolina. I work full time for a judge at a courthouse. I love working out. I love going to the gym. I love playing softball as much as I can. A lot of my daily routine would depend on and revolve around my endometriosis pain. Not only would I have pain during my period, I would have pain all the time. Every day there was a constant cramping or feeling like somebody was just literally squeezing to where I would have to step away. Whether I was at work, or on the softball field, or at the gym, I would have to go take a break until that pain passed. I’ve always wanted to do law enforcement since I was in high school. But I was in pain every day. And I couldn’t let that be something that took my focus away from my job…

[Text on Screen] 
Please see Important Safety Information and the Full Prescribing Information, including the Medication Guide, on this website. 

DARBY:
and now since ORILISSA, I have less endometriosis pain. So now I’m less focused on my pain and more on my goals.

[Text on Screen]
ASK YOUR GYNECOLOGIST IF ORILISSA COULD BE RIGHT FOR YOU. 

[ORILISSA logo]

[Text on Screen/Voiceover]
SAFETY CONSIDERATIONS

Do not use ORILISSA if you are pregnant, have osteoporosis or severe liver disease, take medicines called organic anion transporting polypeptide (OATP) 1B1 inhibitors that are known or expected to significantly increase the blood levels of elagolix (the active ingredient in ORILISSA), or have had a serious allergic reaction to ORILISSA or any of the ingredients in ORILISSA. ORILISSA does not prevent pregnancy. It may alter your period, so watch for other signs of pregnancy. Stop taking ORILISSA if you become pregnant. Ask about proper birth control, as some may affect how ORILISSA works. ORILISSA may affect how some birth control works. ORILISSA can cause serious side effects, including bone loss, abnormal liver tests, suicidal thoughts or behaviors, and worsening mood. Talk to your healthcare provider right away if you notice changes such as jaundice, dark amber-colored urine, suicidal thoughts or actions, depression, or worsening mood.

Please see additional Important Safety Information and the Full Prescribing Information, including Medication Guide, on this website.

US-ORIL-210006