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What is ORILISSA?
ORILISSA is a prescription medicine used to treat moderate to severe pain associated with endometriosis. It is not known if ORILISSA is safe and effective in children.

Do not take ORILISSA if you:
Are pregnant, have osteoporosis, have severe liver disease, are taking medicines called OATP 1B1 inhibitors that are known or expected to significantly increase the blood levels of elagolix, the active ingredient in ORILISSA (ask your HCP if you are not sure if you are taking one of these medicines), or have had a serious allergic reaction to ORILISSA or any of the ingredients in ORILISSA. See the end of the Medication Guide for a complete list of ingredients in ORILISSA. Ask your HCP if you are not sure.

Please see additional Important Safety Information and the Full Prescribing Information, including Medication Guide, on this website.

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Dr. Miller’s ORILISSA STORY

Individual results may vary.

DR. MILLER:
I’m Dr. Chuck Miller. I’m a gynecologic surgeon who specializes in the minimally invasive excision of endometriosis. I perform approximately a half dozen advanced surgeries for endometriosis each week. But I don’t always recommend surgery. Think about it…endometriosis is a chronic disease. What other chronic disease is treated by a surgical option alone? I certainly try to exhaust medical treatment prior to any thoughts of surgical removal of the disease. One of the treatment options that I recommend to my patients is ORILISSA.

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Please see Important Safety Information and the Full Prescribing Information, including the Medication Guide, on this website. 

DR. MILLER:
As of October 2019, ORILISSA has been prescribed to over 30,000 women…and I myself prescribe ORILISSA to patients with moderate to severe pain due to endometriosis. Before prescribing it, I explain to them that ORILISSA doesn’t contain hormones. It’s not a birth control. It’s not an injection. And it’s not surgery. It’s different. It’s a pill that dials estrogen down. After prescribing ORILISSA, I always schedule a follow-up appointment. Just to check in with my patient. We discuss any improvement in her pain levels. Usually, the pain has gone down especially by the third month…that’s when we typically see a difference. As a surgeon, I’m confident in my decision to treat patients with ORILISSA and I’m actually looking forward to treating more patients with ORILISSA when it’s appropriate.

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ASK YOUR GYNECOLOGIST IF ORILISSA COULD BE RIGHT FOR YOU. 

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SAFETY CONSIDERATIONS

Do not use ORILISSA if you are pregnant, have osteoporosis or severe liver disease, take medicines called organic anion transporting polypeptide (OATP) 1B1 inhibitors that are known or expected to significantly increase the blood levels of elagolix (the active ingredient in ORILISSA), or have had a serious allergic reaction to ORILISSA or any of the ingredients in ORILISSA. ORILISSA does not prevent pregnancy. It may alter your period, so watch for other signs of pregnancy. Stop taking ORILISSA if you become pregnant. Ask about proper birth control, as some may affect how ORILISSA works. ORILISSA may affect how some birth control works. ORILISSA can cause serious side effects, including bone loss, abnormal liver tests, suicidal thoughts or behaviors, and worsening mood. Talk to your healthcare provider right away if you notice changes such as jaundice, dark amber-colored urine, suicidal thoughts or actions, depression, or worsening mood.

Please see additional Important Safety Information and the Full Prescribing Information, including Medication Guide, on this website.

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