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What is ORILISSA?
ORILISSA is a prescription medicine used to treat moderate to severe pain associated with endometriosis. It is not known if ORILISSA is safe and effective in children.

Do not take ORILISSA if you:
Are pregnant, have osteoporosis, have severe liver disease, are taking medicines called OATP 1B1 inhibitors that are known or expected to significantly increase the blood levels of elagolix, the active ingredient in ORILISSA (ask your HCP if you are not sure if you are taking one of these medicines), or have had a serious allergic reaction to ORILISSA or any of the ingredients in ORILISSA. See the end of the Medication Guide for a complete list of ingredients in ORILISSA. Ask your HCP if you are not sure.

Please see additional Important Safety Information and the Full Prescribing Information, including Medication Guide, on this website.

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Dr. Shepherd & Angela DISCUSS OPTIONS FOR MODERATE TO SEVERE ENDOMETRIOSIS PAIN

Individual results may vary.

ANGELA:
I’ve been having endometriosis pain since I was about 14… and it was kind of my first period and everything has kind of developed from there. I decided to start to speak up...

DR. SHEPHERD:
Mhm.

ANGELA:
and I went to a lot of doctors, and I’ve had a lot of surgery, but the pain just kept coming back. So, I went to see my gynecologist, and we had a discussion. And at this time, another surgery just wasn’t for me.

DR. SHEPHERD:
And you know, as a gynecologist who is a minimally invasive surgeon, and doing excision surgery…surgery is an option for women, and we have good data on surgery as far as clinical outcomes, but there are some women who surgery is not the answer for them. Or like in your case, you had so many surgeries and you didn’t—

ANGELA:
Right.

DR. SHEPHERD:
want any more.

ANGELA:
At some point, you just have to say, “what now?”

DR. SHEPHERD:
You know there are medical options, and taking medications such as ORILISSA can help patients with their moderate to severe endometriosis pain.

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Please see Important Safety Information and the Full Prescribing Information, including the Medication Guide, on this website. 

ANGELA:
I went to see my gynecologist and she prescribed ORILISSA, and I’m so glad she did because it’s working for me, and it’s helping to relieve my endometriosis pain.

DR. SHEPHERD:
I love to hear that you’ve had both sides, you know, of treatment options, from surgery to medical, but you’ve now found something that works for you, and I hope that other women can hear your story and be empowered by that.

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ASK YOUR GYNECOLOGIST IF ORILISSA COULD BE RIGHT FOR YOU. 

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SAFETY CONSIDERATIONS

Do not use ORILISSA if you are pregnant, have osteoporosis or severe liver disease, take medicines called organic anion transporting polypeptide (OATP) 1B1 inhibitors that are known or expected to significantly increase the blood levels of elagolix (the active ingredient in ORILISSA), or have had a serious allergic reaction to ORILISSA or any of the ingredients in ORILISSA. ORILISSA does not prevent pregnancy. It may alter your period, so watch for other signs of pregnancy. Stop taking ORILISSA if you become pregnant. Ask about proper birth control, as some may affect how ORILISSA works. ORILISSA may affect how some birth control works. ORILISSA can cause serious side effects, including bone loss, abnormal liver tests, suicidal thoughts or behaviors, and worsening mood. Talk to your healthcare provider right away if you notice changes such as jaundice, dark amber-colored urine, suicidal thoughts or actions, depression, or worsening mood.

Please see additional Important Safety Information and the Full Prescribing Information, including Medication Guide, on this website.

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