There has been a change to the Prescribing Information. Click here to see the changes and talk with your doctor for more information.
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What is ORILISSA?
ORILISSA is a prescription medicine used to treat moderate to severe pain associated with endometriosis. It is not known if ORILISSA is safe and effective in children under 18 years of age.
Do not take ORILISSA if you:
Are or may be pregnant, have osteoporosis, have severe liver disease, or take medicines known as strong OATP1B1 inhibitors, such as cyclosporine or gemfibrozil.
Please see additional Important Safety Information and the Full Prescribing Information, including Medication Guide, on this website.
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Dr. Shepherd’s ORILISSA STORY
Individual results may vary.
DR. SHEPHERD:
I’m Dr. Shepherd. I’m a gynecologist who specializes in endometriosis management and I’m highly trained in excision surgery. Endometriosis presents itself in so many different ways and varying degrees from woman to woman. So the right way to manage endometriosis is going to be different for each patient. So, to determine what’s right, I usually start by building trust and establishing a really good relationship to get to know my patient better. I feel that’s really important. So I’ll ask about their medical history, I’ll ask about their symptoms, and their treatment goals. You know, I really want to make sure that they feel that they’re heard. And then we come up with a treatment plan. Often times, surgery isn’t always what’s appropriate for a patient who has moderate to severe endometriosis pain. And I’ll recommend medical management instead. And so for those instances, I may recommend ORILISSA as an option for medical treatment.
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Please see Important Safety Information and the Full Prescribing Information, including the Medication Guide, on this website.
DR. SHEPHERD:
You know, I explain to patients that endometriosis is a chronic condition and is fueled by estrogen, and ORILISSA works by dialing estrogen down. For my patients, I definitely make sure that I explain, as with any treatment, there may be side effects on ORILISSA. Everyone has a different experience with side effects, so I tell my patients to let me know if they have any of those. And if they have any concerns, to please come and see me so that we can address them. I find that at three months, when I have my patients come back in for a scheduled follow-up, that they do have improvement in their pain after starting ORILISSA. So, have that conversation about ORILISSA with your gynecologist and see if it could be right for you.
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ASK YOUR GYNECOLOGIST IF ORILISSA COULD BE RIGHT FOR YOU.
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SAFETY CONSIDERATIONS
Do not use ORILISSA if you are or may be pregnant, have osteoporosis or severe liver disease, or take medicines such as cyclosporine or gemfibrozil. ORILISSA does not prevent pregnancy. It may alter your period, so watch for other signs of pregnancy. Stop taking ORILISSA if you become pregnant. Ask about proper birth control, as some may affect how ORILISSA works. ORILISSA can cause serious side effects, including bone loss, abnormal liver tests, suicidal thoughts or behaviors, and worsening mood. Talk to your healthcare provider right away if you notice changes such as jaundice, dark amber-colored urine, suicidal thoughts or actions, depression, or worsening mood.
Please see additional Important Safety Information and the Full Prescribing Information, including Medication Guide, on this website.
US-ORIL-190820
ORILISSA® (elagolix) is a prescription medicine used to treat moderate to severe pain associated with endometriosis. It is not known if ORILISSA is safe and effective in children under 18 years of age.
ORILISSA may cause serious side effects, including bone loss and effects on pregnancy:
Tell your HCP about all of your medical conditions, including if you:
Tell your HCP about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Especially tell your HCP if you take birth control pills. Your HCP may advise you to change the pills you take or your method of birth control.
ORILISSA can cause serious side effects including:
The most common side effects of ORILISSA include: hot flashes or night sweats, headache, nausea, difficulty sleeping, absence of periods, anxiety, joint pain, depression, and mood changes.
These are not all of the possible side effects of ORILISSA. This is the most important information to know about ORILISSA. For more information, talk to your doctor or HCP.
Take ORILISSA exactly as your HCP tells you. Tell your HCP if you have any side effect that bothers you or that does not go away. Call your HCP for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.
If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.
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Please click here for Full Prescribing Information and Medication Guide.