How Kellyn Did Her Own Research, Kept Thinking About ORILISSA, and Realized It's Not Normal to Be in This Much Pain

[LOGO]

[Text on Screen]
What is ORILISSA?
ORILISSA is a prescription medicine used to treat moderate to severe pain associated with endometriosis. It is not known if ORILISSA is safe and effective in children under 18 years of age.

Individual results may vary.

[Text on Screen]
KELLYN P.
TEXAS

[Text on Screen]
Do not take ORILISSA if you:
Are or may be pregnant, have osteoporosis, have severe liver disease, or take medicines known as strong OATP1B1 inhibitors, such as cyclosporine or gemfibrozil.

Please see additional Important Safety Information and the Full Prescribing Information, including Medication Guide, on this website.

[Text on Screen]
I USED TO BE

Kellyn:
I used to be….

[Text on Screen]
A SKEPTIC

Kellyn:
… a skeptic.

Kellyn:
I had tried other treatments...

Kellyn:
…for my endometriosis pain...

Kellyn:
…and they hadn’t worked, so...

[Text on Screen]
SO WHY WOULD I TRY ORILISSA® (elagolix)?

Kellyn:
…why would I try ORILISSA?

Kellyn:
My gynecologist explained...

Kellyn:
…that my endometriosis pain is...

[Text on Screen]
TRIGGERED

Kellyn:
…triggered by something that my body naturally makes called...

[Text on Screen]
ESTROGEN

Kellyn:
…estrogen. And, as…

[Text on Screen]
ESTROGEN

Kellyn:
…long as my body keeps making estrogen…

[Text on Screen]
PAIN

Kellyn:
…I’d be in pain. But because…

Kellyn:
…estrogen does a lot of…

[Text on Screen]
GOOD THINGS

Kellyn:
…good things, she didn’t want to get rid of it completely.

Kellyn:
That’s why she…

[Text on Screen]
RECOMMENDED

Kellyn:
…had recommended…

[Text on Screen]
ORILISSA® (elagolix)

Kellyn:
…ORILISSA…

[Text on Screen]
DIALS

Kellyn:
…because it’s a pill that dials…

[Text on Screen]
DOWN

Kellyn:
…down…

[Text on Screen]
ESTROGEN

Kellyn:
…estrogen…

[Text on Screen]
TO

Kellyn:
…to…

[Text on Screen]
DIFFERENT

Kellyn:
…different…

[Text on Screen]
LEVELS

Kellyn:
…levels…

[Text on Screen]
Please see Important Safety Information and the Full Prescribing Information, including the Medication Guide, on this website.

Kellyn:
. ..depending on the dose you take.

[Text on Screen]
Please see Important Safety Information and the Full Prescribing Information, including the Medication Guide, on this website.

Kellyn:
It made sense, but I still didn’t think...

[Text on Screen]
Please see Important Safety Information and the Full Prescribing Information, including the Medication Guide, on this website.

Kellyn:
...ORILISSA would actually work.

[Text on Screen]
MY OWN RESEARCH

Kellyn:
I needed to do my own research....

Kellyn:
...so I went online and saw that...

[Text on Screen]
TENS OF THOUSANDS

Kellyn:
...tens of thousands...

[Text on Screen]
OF WOMEN

Kellyn:
...of women had been...

Kellyn:
...prescribed ORILISSA.

Kellyn:
I read, of course, like, the side effects and...

[Text on Screen]
PROS

Kellyn:
...the pros…

[Text on Screen]
CONS

Kellyn:
...and cons to it.

[Text on Screen]
THAT RESEARCH HELPED ME DETERMINE

Kellyn:
That research is what helped me determine that I was...

Kellyn:
...going to try ORILISSA. Now...

[Text on Screen]
RELIEVING MY PAIN

Kellyn:
...ORILISSA is relieving my pain.

[Text on Screen]
IT’S WORKING

Kellyn:
It’s working...

[Text on Screen]
FOR ME

Kellyn:
...for me.

Kellyn:
I wanted to share my story with other women...

[Text on Screen]
BEING IN PAIN

Kellyn:
...because being in pain is...

[Text on Screen]
NOT NORMAL

Kellyn:
...not normal.

Kellyn:
You gotta keep trying and keep fighting...

[Text on Screen]
PAIN RELIEF

Kellyn:
...to find pain relief.

Kellyn:
You never really know what’s gonna come out on the other...

[Text on Screen]
UNLESS YOU TRY

Kellyn:
. ..side unless you try it.

[Text on Screen]
IT CAN BE WORTH IT

Kellyn:
It can be worth it.

Kellyn:
I tried ORILISSA and...

[Text on Screen]
I’M NOT A SKEPTIC ANYMORE

Kellyn:
...I’m not a skeptic anymore.

[Text on Screen]
THINKING ABOUT TRYING ORILISSA (elagolix)?

[Text on Screen]
TALK TO YOUR GYNECOLOGIST TO SEE IF IT COULD BE RIGHT FOR YOU.

[ORILISSA logo]

[Text on Screen/Voiceover]
SAFETY CONSIDERATIONS

Do not use ORILISSA if you are or may be pregnant, have osteoporosis or severe liver disease, or take medicines such as cyclosporine or gemfibrozil. ORILISSA does not prevent pregnancy. It may alter your period, so watch for other signs of pregnancy. Stop taking ORILISSA if you become pregnant. Ask about proper birth control, as some may affect how ORILISSA works. ORILISSA can cause serious side effects, including bone loss, abnormal liver tests, suicidal thoughts or behaviors, and worsening mood. Talk to your healthcare provider right away if you notice changes such as jaundice, dark amber-colored urine, suicidal thoughts or actions, depression, or worsening mood.

Please see additional Important Safety Information and the Full Prescribing Information, including Medication Guide, on this website.

US-ORIL-200172

USE

ORILISSA® (elagolix) is a prescription medicine used to treat moderate to severe pain associated with endometriosis. It is not known if ORILISSA is safe and effective in children under 18 years of age.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about ORILISSA?

ORILISSA may cause serious side effects, including bone loss and effects on pregnancy:

  • Bone Loss (decreased Bone Mineral Density [BMD])
    While you are taking ORILISSA, your estrogen levels will be low. This can lead to BMD loss. Your BMD may improve after stopping ORILISSA, but may not recover completely. It is unknown if these bone changes could increase your risk for broken bones as you age. Your healthcare provider (HCP) may order a DXA scan to check your BMD.
  • Effects on Pregnancy
    Do not take 
    ORILISSA if you are trying to become or are pregnant, as your risk for early pregnancy loss may increase. If you think you are pregnant, stop taking ORILISSA right away and call your HCP. ORILISSA may change your menstrual periods (irregular bleeding or spotting, a decrease in menstrual bleeding, or no bleeding at all), making it hard to know if you are pregnant. Watch for other signs of pregnancy, such as breast tenderness, weight gain, and nausea. ORILISSA does not prevent pregnancy. You will need to use effective hormone-free birth control (such as condoms or spermicide) while taking ORILISSA and for one week after stopping ORILISSA. Birth control pills that contain estrogen may make ORILISSA less effective. It is unknown how well ORILISSA works while on progestin-only birth control.

Do not take ORILISSA if you:

  • Are or may be pregnant, have osteoporosis, have severe liver disease, or take medicines known as strong OATP1B1 inhibitors, such as cyclosporine or gemfibrozil. If you are unsure if you are taking one of these medicines, ask your HCP.

What should I tell my HCP before taking ORILISSA?

Tell your HCP about all of your medical conditions, including if you:

  • Have or have had broken bones, have other conditions, or take medicines that may cause bone problems; have or have had depression, mood problems, or suicidal thoughts or behavior; have liver problems; think you may be pregnant; or are breastfeeding or plan to be. It is unknown if ORILISSA passes into breast milk. Talk to your HCP about the best way to feed your baby if you take ORILISSA.

Tell your HCP about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Especially tell your HCP if you take birth control pills. Your HCP may advise you to change the pills you take or your method of birth control.

What are the possible side effects of ORILISSA?

ORILISSA can cause serious side effects including:

  • Suicidal thoughts, actions, or behavior, and worsening of mood. Call your HCP right away, or call 911 if an emergency, if you have any of these symptoms, especially if they are new, worse, or bother you: thoughts about suicide or dying, try to commit suicide, new or worse depression or anxiety, or other unusual changes in behavior or mood. You or your caregiver should pay attention to any changes, especially sudden changes in your mood, behaviors, thoughts, or feelings.
  • Abnormal liver tests. Call your HCP right away if you have any of these signs and symptoms of liver problems: yellowing of the skin or the whites of the eyes (jaundice), dark amber-colored urine, feeling tired, nausea and vomiting, generalized swelling, right upper stomach area pain, or bruising easily.

The most common side effects of ORILISSA include: hot flashes or night sweats, headache, nausea, difficulty sleeping, absence of periods, anxiety, joint pain, depression, and mood changes.

These are not all of the possible side effects of ORILISSA. This is the most important information to know about ORILISSA. For more information, talk to your doctor or HCP.

Take ORILISSA exactly as your HCP tells you. Tell your HCP if you have any side effect that bothers you or that does not go away. Call your HCP for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.

If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.


US-ORIL-200129

Please click here for Full Prescribing Information and Medication Guide.

 

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about ORILISSA?

ORILISSA may cause serious side effects, including bone loss and effects on pregnancy:

USE

ORILISSA® (elagolix) is a prescription medicine used to treat moderate to severe pain associated with endometriosis. It is

USE

ORILISSA® (elagolix) is a prescription medicine used to treat moderate to severe pain associated with endometriosis. It is not known if ORILISSA is...

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about ORILISSA?

ORILISSA may cause serious side effects, including bone loss and effects on pregnancy:

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about ORILISSA?

ORILISSA may cause serious side effects, including bone loss and effects on pregnancy:

USE

ORILISSA® (elagolix) is a prescription medicine used to treat moderate to severe pain associated with endometriosis. It is

USE

ORILISSA® (elagolix) is a prescription medicine used to treat moderate to severe pain associated with endometriosis. It is not known if ORILISSA is...

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about ORILISSA?

ORILISSA may cause serious side effects, including bone loss and effects on pregnancy:

USE

ORILISSA® (elagolix) is a prescription medicine used to treat moderate to severe pain associated with endometriosis. It is not known if ORILISSA is safe and effective in children under 18 years of age.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about ORILISSA?

ORILISSA may cause serious side effects, including bone loss and effects on pregnancy:

  • Bone Loss (decreased Bone Mineral Density [BMD])
    While you are taking ORILISSA, your estrogen levels will be low. This can lead to BMD loss. Your BMD may improve after stopping ORILISSA, but may not recover completely. It is unknown if these bone changes could increase your risk for broken bones as you age. Your healthcare provider (HCP) may order a DXA scan to check your BMD.
  • Effects on Pregnancy
    Do not take 
    ORILISSA if you are trying to become or are pregnant, as your risk for early pregnancy loss may increase. If you think you are pregnant, stop taking ORILISSA right away and call your HCP. ORILISSA may change your menstrual periods (irregular bleeding or spotting, a decrease in menstrual bleeding, or no bleeding at all), making it hard to know if you are pregnant. Watch for other signs of pregnancy, such as breast tenderness, weight gain, and nausea. ORILISSA does not prevent pregnancy. You will need to use effective hormone-free birth control (such as condoms or spermicide) while taking ORILISSA and for one week after stopping ORILISSA. Birth control pills that contain estrogen may make ORILISSA less effective. It is unknown how well ORILISSA works while on progestin-only birth control.

Do not take ORILISSA if you:

  • Are or may be pregnant, have osteoporosis, have severe liver disease, or take medicines known as strong OATP1B1 inhibitors, such as cyclosporine or gemfibrozil. If you are unsure if you are taking one of these medicines, ask your HCP.

What should I tell my HCP before taking ORILISSA?

Tell your HCP about all of your medical conditions, including if you:

  • Have or have had broken bones, have other conditions, or take medicines that may cause bone problems; have or have had depression, mood problems, or suicidal thoughts or behavior; have liver problems; think you may be pregnant; or are breastfeeding or plan to be. It is unknown if ORILISSA passes into breast milk. Talk to your HCP about the best way to feed your baby if you take ORILISSA.

Tell your HCP about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Especially tell your HCP if you take birth control pills. Your HCP may advise you to change the pills you take or your method of birth control.

What are the possible side effects of ORILISSA?

ORILISSA can cause serious side effects including:

  • Suicidal thoughts, actions, or behavior, and worsening of mood. Call your HCP right away, or call 911 if an emergency, if you have any of these symptoms, especially if they are new, worse, or bother you: thoughts about suicide or dying, try to commit suicide, new or worse depression or anxiety, or other unusual changes in behavior or mood. You or your caregiver should pay attention to any changes, especially sudden changes in your mood, behaviors, thoughts, or feelings.
  • Abnormal liver tests. Call your HCP right away if you have any of these signs and symptoms of liver problems: yellowing of the skin or the whites of the eyes (jaundice), dark amber-colored urine, feeling tired, nausea and vomiting, generalized swelling, right upper stomach area pain, or bruising easily.

The most common side effects of ORILISSA include: hot flashes or night sweats, headache, nausea, difficulty sleeping, absence of periods, anxiety, joint pain, depression, and mood changes.

These are not all of the possible side effects of ORILISSA. This is the most important information to know about ORILISSA. For more information, talk to your doctor or HCP.

Take ORILISSA exactly as your HCP tells you. Tell your HCP if you have any side effect that bothers you or that does not go away. Call your HCP for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.

If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.


US-ORIL-200129

Please click here for Full Prescribing Information and Medication Guide.